ID   HSLAM11    standard; DNA; HUM; 958 BP.
XX
AC   L37747;
XX
SV   L37747.1
XX
DT   23-NOV-1994 (Rel. 41, Created)
DT   15-FEB-2000 (Rel. 62, Last updated, Version 7)
XX
DE   Homo sapiens lamin B1 gene, exon 11, complete cds.
XX
KW   lamin B1.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Primates; Catarrhini; Hominidae; Homo.
XX
RN   [1]
RP   1-958
RX   MEDLINE; 96044426.
RA   Lin F., Worman H.J.;
RT   "Structural organization of the human gene (LMNB1) encoding nuclear lamin
RT   B1";
RL   Genomics 27(2):230-236(1995).
XX
RN   [2]
RP   1-958
RX   MEDLINE; 98042369.
RA   Lin F., Worman H.J.;
RT   "Expression of nuclear lamins in human tissues and cancer cell lines and
RT   transcription from the promoters of the lamin A/C and B1 genes";
RL   Exp. Cell Res. 236(2):378-384(1997).
XX
RN   [3]
RP   1-958
RA   Worman W.J.;
RT   ;
RL   Submitted (28-NOV-1994) to the EMBL/GenBank/DDBJ databases.
RL   Medicine, Columbia University, 630 West 168th Street, New York, NY 10032,
RL   USA
XX
RN   [4]
RC   Sequence update by submitter
RP   1-958
RA   Worman W.J.;
RT   ;
RL   Submitted (13-MAY-1997) to the EMBL/GenBank/DDBJ databases.
RL   Medicine, Columbia University, 630 West 168th Street, New York, NY 10032,
RL   USA
XX
DR   SWISS-PROT; P20700; LAM1_HUMAN.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..958
FT                   /chromosome="5"
FT                   /db_xref="taxon:9606"
FT                   /organism="Homo sapiens"
FT                   /map="5q23.2-31.3"
FT   mRNA            join(L37737.2:<1677..2035,L37738.1:479..635,
FT                   L37739.1:300..425,L37740.1:248..418,L37741.1:23..148,
FT                   L37742.1:103..323,L37743.1:78..303,L37744.1:205..309,
FT                   L37745.1:108..227,L37746.1:124..231,157..946)
FT                   /product="lamin B1"
FT   CDS             join(L37737.2:1677..2035,L37738.1:479..635,
FT                   L37739.1:300..425,L37740.1:248..418,L37741.1:23..148,
FT                   L37742.1:103..323,L37743.1:78..303,L37744.1:205..309,
FT                   L37745.1:108..227,L37746.1:124..231,157..198)
FT                   /codon_start=1
FT                   /db_xref="SWISS-PROT:P20700"
FT                   /product="lamin B1"
FT                   /protein_id="AAC37575.1"
FT                   /translation="MATATPVPPRMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAV
FT                   YIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQ
FT                   IELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDL
FT                   EDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRK
FT                   HETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEM
FT                   NTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLT
FT                   DKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVT
FT                   VSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKN
FT                   TSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKN
FT                   QNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTP
FT                   RASNRSCAIM"
FT   exon            157..946
FT                   /number=11
FT   3'UTR           199..946
FT   polyA_signal    930..935
XX
SQ   Sequence 958 BP; 285 A; 127 C; 186 G; 360 T; 0 other;
     aaaagaaaag gttagaaaga tgagagatga taaagggtcc atttgaggtt aggtaatatg        60
     gtttggtatc cctgtagtta aaagtttttg tcttatttta gaatactgtg atctatttct       120
     ttagtattaa tttttccttc tgttttcctc atctagggaa ccccaagagc atccaataga       180
     agctgtgcaa ttatgtaaaa ttttcaactg tcttcctcaa aataaagaag tatggtaatc       240
     tttacctgta tacagtgcag agccttctca gaagcacaga atatttttat atttccttta       300
     tgtgaatttt taagctgcaa atctgatggc cttaatttcc tttttgacac tgaaagtttt       360
     gtaaaagaaa tcatgtccat acactttgtt gcaagatgtg aattattgac actgaactta       420
     ataactgtgt actgttcgga aggggttcct caaatttttt gacttttttt gtatgtgtgt       480
     tttttctttt tttttaagtt cttatgagga ggggagggta aataaaccac tgtgcgtctt       540
     ggtgtaattt gaagattgcc ccatctagac tagcaatctc ttcattattc tctgctatat       600
     ataaaacggt gctgtgaggg aggggaaaag catttttcaa tatattgaac ttttgtactg       660
     aatttttttg taataagcaa tcaaggttat aatttttttt aaaatagaaa ttttgtaaga       720
     aggcaatatt aacctaatca ccatgtaagc actctggatg atggattcca caaaacttgg       780
     ttttatggtt acttcttctc ttagattctt aattcatgag gagggtgggg gagggaggtg       840
     gagggaggga agggtttctc tattaaaatg cattcgttgt gttttttaag atagtgtaac       900
     ttgcttaaat ttcttatgtg acattaacaa ataaaaaagc tcttttaata ttagataa         958
//